Showing posts with label Vitamin D. Show all posts
Showing posts with label Vitamin D. Show all posts

Sunday, May 24, 2009

Calcium and vitamin D enhance heart health benefits of weight loss

Weight loss and reduced waist circumference are related to an improvement in heart health and factors related to metabolic syndrome. According to a new study, supplementing with calcium and vitamin D during weight loss enhances heart health benefits in women with typically low calcium intake.

Recent research has shown that overweight individuals with low calcium and dairy consumption are at increased risk of developing metabolic syndrome. The findings suggest that adequate calcium intake could create a healthier metabolic profile similar to a balanced diet and regular exercise. In a new study, researchers investigated this issue by testing cardiovascular benefits of long-term calcium supplementation in women with usual low calcium intake. Healthy, overweight or obese women with a daily calcium intake of less than 800 mg/day were randomly assigned to 1 of 2 groups: the group consuming 2 tablets/day of a calcium + vitamin D supplement (600 mg elemental calcium and 200 IU vitamin D/tablet) or the group consuming placebo. Both groups completed a 15-week reduced calorie weight-loss program. Significant decreases in LDL cholesterol levels, as well as the ratios of Total to LDL and LDL to HDL were seen the calcium +D group. These changes were independent of the changes due to fat loss and reduced waist circumference. A tendency for more beneficial changes in HDL cholesterol, triglycerides, and total cholesterol was also observed in the calcium +D group.This was the first study to show that consumption of calcium +D during weight- loss enhances the beneficial effect of body weight loss on cardiovascular risk factors in overweight women with typically low calcium intake.

Source: Supplementation with calcium + vitamin D enhances the beneficial effect of weight loss on plasma lipid and lipoprotein concentrations, Geneviève C Major, Francine Alarie, Jean Doré, Sakouna Phouttama and Angelo Tremblay, American Journal of Clinical Nutrition, Vol. 85, No. 1, 54-59, January 2007

Supplemental vitamin D and calcium reduces risk of diabetes

The incidence of type-2 diabetes is lower among women who get adequate calcium and supplement with vitamin D. Researchers used data from the Nurses Health Study, which includes over 83,000 women, to study the relationship of calcium and vitamin D intake to type-2 diabetes.


After 20 years of follow-up, it was concluded that a combined daily intake of over 1,200 mg of calcium and more than 800 IU of vitamin D was associated with a 33 percent lower risk of type-2 diabetes. Interestingly, dietary vitamin D intake did not appear to provide any statistically significant benefit. But the women who supplemented with at least 400 IU of vitamin D had a 13% lower risk of diabetes when compared to those who took less than 100 IU per day. Both dietary and supplemental calcium resulted in decreased risk of type-2 diabetes, and those with overall intakes above 1,200 mg had a 21% lower risk than those who got less than 600 mg per day. Elevated intakes of calcium and vitamin D, especially from supplements, are significantly associated with lower incidence of type-2 diabetes.


Source: Vitamin D and Calcium Intake in Relation to Type 2 Diabetes in Women, Anastassios G. Pittas et al, Diabetes Care 29:650-656, 2006

My recommendation: Active Calcium

Vitamin D and calcium supplementation reduces cancer risk

A four year clinical was done that involved nearly 1200 women. This is the kind of study physicians love and always talk about when it comes to pharmaceutical trials. However, very few of them realize that there are these kinds of studies regarding the health benefits of taking supplements. Subjects were assigned to take 1400 mg of calcium alone, or 1400 mg of calcium plus 1100 IU of vitamin D, or a placebo. After only 4 years, the risk of developing any type of cancer was 60% lower in the vitamin D group. If you excluded the cancers diagnosed in the first year because these cancers were most likely already present before the study, there was a 77% reduction in all types of cancer in the vitamin D group.

The researchers pointed out that vitamin D has an effect on at least 200 human genes and is critical in the normal functioning of our immune system and cell division. When there is less than an optimal level of vitamin D, the regulatory process involving cell proliferation and differentiation becomes defective. This can lead to abnormal cell division and thus cancer growth. However, if individuals simply supplement their diet with 1100 IU of vitamin D, they can significantly decrease their risk of all cancers.

Source: Dr. Strand Health Nuggets (newsletter@Bionutrition.org)

Vitamin D prevents and improves several diseases

Vitamin D has been shown to suppress inflammation in diseases like rheumatoid arthritis, congestive heart failure, and even stroke. Clinical studies have also shown that there is a decrease in the risk of both type 1 and 2 diabetes in individuals who supplement with vitamin D. There are far fewer falls in those elderly patients who supplement with vitamin D at this optimal level. Another important aspect is the fact that vitamin D is required for proper immune function. It is also known that those individuals who live in higher latitudes contract multiple sclerosis at far higher rates than those who obtain more sunshine throughout the year. Studies with supplementing even 400 IU of vitamin D have shown significant reduction in the risk of developing multiple sclerosis. The question is now arising that we need to actually be providing our bodies with much more vitamin D than we previously thought.

Source: Dr. Strand Health Nuggets (newsletter@Bionutrition.org)

Inflammation and Vitamin D

Oxidative stress and inflammation is an underlying factor in the development of numerous age-related diseases. In clinical trials, vitamin D has been shown to suppress what is referred to as pro-inflammatory cytokines. This offers additional protection against conditions ranging from rheumatoid arthritis, prediabetes, heart failure, stroke, and heart disease.
It has become evident that those individuals who live in higher altitudes contract multiple sclerosis at much higher rates than those living where they get sunshine throughout the year. Scientists have identified specific vitamin D receptors in the white matter of the brain. The reduction in inflammation, which is the result of adequate vitamin D, may play a role in protecting you against developing multiple sclerosis.

Source: Dr. Strand Health Nuggets (newsletter@Bionutrition.org)

Low Vitamin D levels increase cardiovascular risk

A report in the Archives of Internal Medicine (June 11,2007) added more evidence in the link of low vitamin D levels and heart disease. These researchers measured the 25-Hydroxy Vitamin D levels in over 15,000 women. Those women who had the lowest levels of vitamin D had significantly higher prevalence of hypertension, diabetes, and elevated triglyceride levels (the other fat in the blood other than cholesterol). These are all risk factors for heart disease and strokes.
These researchers again pointed out the fact that low vitamin D levels carry a significant risk factor to our health. They concluded that current intake of vitamin D is far to low for optimal health. This is why I recommend that my patients should get their vitamin D levels checked and act accordingly. First, to bring their vitamin D levels back up to the recommended level (at least greater than 50 ng/ml) and second, to maintain these levels by taking at least 1,000 to 1,200 IU of vitamin D in supplementation.

Source: Dr. Strand Health Nuggets (newsletter@Bionutrition.org)

Friday, May 22, 2009

Vitamin D protects against stroke

Stroke is the fourth leading cause of death (140,000 per year in the US) in the US and Canada. Adverse drug reactions are the third leading cause of death (180,000 deaths per year in the US) in the US and Canada. Everyone is very concerned about having a stroke because of the major disability it can cause.
A study published in September 2008, revealed that for every small decrease in blood levels of vitamin D there was a startling 86% increase in fatal strokes. The researchers concluded that low levels of 25 hydorxyvitamin D levels are independently predictive of fatal strokes and they suggest that vitamin D supplementation is a promising approach in the prevention of strokes.

Source: Dr. Strand Health Nuggets (newsletter@Bionutrition.org)